# The Life Sciences AI Handbook

> AI for Biomedical Discovery, Biotechnology, and Translational Research.

## About

The Life Sciences AI Handbook is an open-access reference by Bryan Tegomoh, MD, MPH. It covers AI systems for biomedical discovery, biotechnology, molecular design, therapeutics, cellular systems, laboratory automation, evaluation, reproducibility, and researcher practice. DOI: pending.

## Canonical Site

https://lifesciencesaihandbook.com/

## Key Pages

- Homepage: https://lifesciencesaihandbook.com/
- Executive Summary: https://lifesciencesaihandbook.com/executive-summary.html
- How to Read: https://lifesciencesaihandbook.com/how-to-read.html
- Scope and Limitations: https://lifesciencesaihandbook.com/scope-limitations.html
- AI for the Life Sciences: https://lifesciencesaihandbook.com/foundations/ai-for-life-sciences.html
- Foundation Models for Biology: https://lifesciencesaihandbook.com/foundations/foundation-models.html
- Protein Structure Prediction: https://lifesciencesaihandbook.com/molecular/protein-structure.html
- Protein Design and Engineering: https://lifesciencesaihandbook.com/molecular/protein-design.html
- Antibody and Biologic Design: https://lifesciencesaihandbook.com/molecular/antibodies.html
- Nucleic Acid and Genome Models: https://lifesciencesaihandbook.com/molecular/genome-models.html
- Target Identification and Prioritization: https://lifesciencesaihandbook.com/therapeutics/targets.html
- Small Molecule Generation and ADMET: https://lifesciencesaihandbook.com/therapeutics/small-molecules.html
- Single-Cell Foundation Models: https://lifesciencesaihandbook.com/cells/single-cell-models.html
- Spatial Omics and Tissue Models: https://lifesciencesaihandbook.com/cells/spatial-omics.html
- Self-Driving Laboratories: https://lifesciencesaihandbook.com/automation/self-driving-labs.html
- Agentic Science Workflows: https://lifesciencesaihandbook.com/automation/agentic-workflows.html
- Benchmarks for Bio AI: https://lifesciencesaihandbook.com/governance/benchmarks.html
- Reproducibility and Open Science: https://lifesciencesaihandbook.com/governance/reproducibility.html
- Information Hazards in Capability Research: https://lifesciencesaihandbook.com/governance/information-hazards.html
- Model and Dataset Index: https://lifesciencesaihandbook.com/appendices/model-dataset-index.html
- References: https://lifesciencesaihandbook.com/references.html
- How to Cite: https://lifesciencesaihandbook.com/how-to-cite.html

## Citation

Tegomoh, B. (2026). The Life Sciences AI Handbook: AI for Biomedical Discovery, Biotechnology, and Translational Research. DOI pending. URL: https://lifesciencesaihandbook.com/

## License

CC BY 4.0